Matthew J. Delano, M.D., Ph.D.

 

RESEARCH INTEREST:

PGY 6 Categorical Surgery Resident who has completed a T32 Research Fellowship in the Laboratory of Inflammation Biology and Surgical Science under the direction of Dr. Lyle L. Moldawer, in the Department of Surgery at the University of Florida. Dr. Delano has also earned a doctoral degree with a concentration in Immunology, from the Department of Immunology and Microbiology through the Interdisciplinary Program in Biomedical Sciences at the University of Florida. After finishing his qualifying exam, entitled Impact of Immature Myeloid Cells in Sepsis in the fall of 2006, Dr. Delano successfully defend his thesis titled, Impact of Myeloid Derived Suppressor Cells During Polymicrobial Sepsis, and graduated in the spring of 2008.

His research interest before coming to the University of Florida focused on the role of chemokine signaling in pancreatic cancer metastasis while working in the Ronald Hirshberg Translational Pancreatic Cancer Laboratory under the direction of Dr. Howard Reber, at The David Geffen School of Medicine at UCLA.  At present, Dr. Delano’s research interests have shifted focus to concentrate on the immune responses that occur during sepsis.  His current projects include investigating the interactions of T lymphocytes, dendritic cells, and immature myeloid cells and their role in the development and propagation of the sepsis syndrome.  In addition he is also investigating the human inflammatory reaction to trauma, sepsis, and cardiopulmonary bypass by evaluating the genomic, proteomic, and cellular immune phenotypes that result from these various insults.



CURRENT PROJECTS: 

1.)    To determine the role that T regulatory lymphocytes play in the development and propagation of the sepsis syndrome.

 2.)    To investigate novel immature myeloid cell populations that have immune modulatory effects during the sepsis syndrome.

 3.)    To investigate the immunomodulatory effects that sepsis has on the host immune system and how those effects can be ameliorated with various therapeutic interventions.

 4.)    To determine the human genomic and proteomic responses to cardiopulmonary bypass and elucidate the elements that mediate systemic inflammation.

 5.)    To use the prospectively collected data compiled by the Inflammation and the Host Response to Injury collaborative research program and determine what genomic and proteomic elements predispose trauma patients to a poor outcome.

AWARDS:

         Finalist:  A.E. Baue Research Award.

Selected as one of the top 10 abstracts out of over 500 abstracts at the 7th World Congress on Trauma, Shock, Inflammation and Sepsis.

M.J. Delano, P.O. Scumpia, K. O’Malley, J. Wynn, and L. Moldawer. Sepsis Reprograms Bone Marrow Hematopoiesis Toward The Myeloid Lineage In A MyD88 And TRIF Dependent Manner. Accepted Abstract and Oral Presentation. 7th World Congress on Trauma, Shock, Inflammation and Sepsis – TSIS 2007, March 13-17, 2007, Munich, Germany.           

            Recipient: clinical/translational Science  Research Award.

            M.J. Delano, G.M. Janelle, P.O. Scumpia, K. O’Malley, R. Ungaro, C.L. Tannahill, E.D. Staples, T. Martin, L.L. Moldawer, and P.J. Hess. Aprotinin Attenuates The Immuno-inflammatory Response And Alters Blood Monocyte Gene Expression Following Cardiopulmonary Bypass. Award Received: April 20, 2007, Department of General Surgery, University of Florida School of Medicine, Gainesville, FL. 

Recipient: Travel Award “Innate Immunity: Receptors, Response, and Regulation”

Matthew J. Delano, M.D., Azra Bihorac, M.D., Philip O. Scumpia, B.S., Avery B, Nathens, M.D., Ronald G. Maier, M.D., Joseph A. Layon, M.D., Lyle L. Moldawer, Ph.D. Early Genomic and Proteomic Changes in Trauma Patients With Acute Kidney Injury Suggest Early Immune Dysfunction. Accepted Abstract and Poster Presentation, Innate Immunity Meeting, SLB, ISER, San Antonio, TX.  November 9-11, 2006. 

Recipient:  The Dr. Herman Brown Award for Excellence in the Study of the Art and Science of surgery.  Awarded for excellence in both patient care and surgical research.   Award Received: May 22, 2003, Temple University School of Medicine, Department of General Surgery. 

Recipient:  Association of Academic Surgery 2003 Student Research Award.

Delano MJ, Duffy JP, Fisher C, Hines OJ, Reber HA: Cellular and Molecular Expression of CXCR4 in Human Pancreatic Cancer Cell Lines: Department of Surgery, The David Geffen School of Medicine at the University of California, Los Angeles, CA. Abstract Accepted: March 28, 2003, Association of Academic Surgery 2003 Student Research Award 

Recipient:  2003 Temple University School of Medicine Student Research day Award

Delano MJ, Duffy JP, Fisher C, Hines OJ, Reber HA: Cellular and Molecular Expression of CXCR4 in Human Pancreatic Cancer Cell Lines: Department of Surgery, The David Geffen School of Medicine at the University of California, Los Angeles, CA; Department of Surgery, Temple University School of Medicine, Philadelphia, PA. Oral Poster Presentation: April 16, 2003, Temple University School of Medicine Student Research Award 2003 

Nominated:  Association of Academic Surgery 2002 Medical Student Research Award.

Delano MJ, Duffy JP, Hines OJ, Reber HA: The role of CXCR4 and SDF-1 in pancreatic cancer invasion and metastasis: Department of Surgery, The David Geffen School of Medicine at the University of California, Los Angeles, CA

Submitted: March 29, 2002, Association of Academic Surgery 2002 Student Research Award.

 BIBLIOGRAPHY:

 

Publications:

1.       Azra Bihorac, Matthew Delano, Andrea Gabrielli, Avery B. Nathens, Ronald V. Maier, A. Joseph Layon, and Lyle L Moldawer. Incidence, clinical predictors and outcome of acute kidney injury among trauma patients. (Manuscript in Preparation, 2008)

2.       Delano MJ, Janelle GM, Scumpia PO, O’Malley K, Ungaro R, Tannahill CL, Staples ED, Martin T, Moldawer LL, Hess PJ. The Effect of Aprotinin on the Immuno-inflammatory Response and Blood Monocyte Gene Expression in Response to Cardiopulmonary Bypass. (Manuscript in Preparation, 2008)

3.       Matthew J. Delano, Kindra M. Kelly-Scumpia, Robert D. Winfield, Philip O. Scumpia, Alex G. Cuenca, Phillips B. Harrington, Elizabeth Warner, Clayton E. Mathews, Drake Laface, Paul G. Heyworth, Robert M. Strieter, and Lyle L. Moldawer. Bone Marrow Neutrophil Mobilization Is Dependent On CXCL12 Signaling During Polymicrobial Infection. (Manuscript in preparation, 2008)

4.       Delano MJ, Scumpia PO, Weinstein JS, Kelly-Scumpia KM, O’Malley KA, Wynn JL, Winfield RD, Moreno CO, Ramphal R, Gabrilovich DI, Reeves WH, Clare-Salzler M, Moldawer LL.  IL-4, IL-10, and CCR2 Signaling Do Not Contribute to the Increased Myeloid Derived Suppressor Cell Numbers or Function During Polymicrobial Sepsis. (Manuscript under revision for resubmission, 2009) 

5.       Darwin Ang, Eileen Bulger, Ronald Maier, Joseph Cuschieri, Matthew Delano, Keir Warner, Laura Hennessy. The Impact of Hypertonic Saline Resuscitation on the Gene Expression Profile of Critically Injured Patients. (Submitted, under review, Annals of Surgery 2008)
 

6.       Matthew J. Delano, Steven N. Hochwald, Christopher A. Garces, Stephen R. Grobmyer, Characterization of Peri-operative Bleeding and Transfusion Utilization in a Modern Series of Pancreaticoduodenectomies. (Submitted, under review, Digestive Disease Surgery, 2008)
 

7.       Steven N. Hochwald, Stephen R. Grobmyer, Eleanor Curran, David A. Bloom, Matthew J. Delano, Alan W. Hemming, Kevin E. Behrns, Stephen B. Vogel. Braun enteroenterostomy is associated with reduced delayed gastric emptying and early resumption of oral feeding following pancreaticoduodenectomy. (Submitted, under review, American Journal of Surgery, 2008)  

8.       Robert D. Winfield, Matthew J. Delano, David J. Dixon, William S. Schierding, Juan C. Cendan, Lawrence Lottenberg, Douglas Hayden, M. Cecilia Lopez, Henry V. Baker, J. Perren Cobb, Lyle L. Moldawer, Ronald V. Maier, and Joseph Cuschieri. Differences in Outcome between Obese and Non-Obese Patients Following Severe Blunt Trauma are Not Consistent with an Early Inflammatory Genomic Response. (2nd Submission with revisions, Critical Care Medicine 2008) 

9.       Kalyan Pande, Roanna Ueda, Todd Machemer, Manjiri Sathe, Van Tsai, Elena Brin, Matthew J. Delano, Nico Van Rooijen, Terrill K. McClanahan, Lyle L. Moldawer, James E. Talmadge, Joseph H. Phillips, Drake M. LaFace.  Cancer-induced increase in and activation of CD11b+Gr-1+ cells predisposes hosts to anaphylactoid-type reactions. (Submitted, under review, Mol. Theraputics 2008) 

10.      Winfield RD, Delano MJ, Pande K, Scumpia PO, Laface D, Moldawer LL. Myeloid-derived suppressor cells in cancer cachexia syndrome: a new explanation for an old problem. JPEN J Parenter Enteral Nutr. 2008 Nov-Dec;32(6):651-5. 

11.      Wynn JL, Scumpia PO, Winfield RD, Delano MJ, Kelly-Scumpia K, Barker T, Ungaro R, Levy O, Moldawer LL. Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists. Blood. 2008 Sep 1;112(5):1750-8. Epub 2008 Jun 30. 

12.     Scumpia PO, Delano MJ, Kelly-Scumpia KM, Weinstein JS, Wynn JL, Winfield RD, Xia C, Chung CS, Ayala A, Atkinson MA, Reeves WH, Clare-Salzler MJ, Moldawer LL. Treatment with GITR agonistic antibody corrects adaptive immune dysfunction in sepsis. Blood. 2007 Nov 15;110(10):3673-81. Epub 2007 Aug 9. 

13.     Wynn JL, Scumpia PO, Delano MJ, O'Malley KA, Ungaro R, Abouhamze A, Moldawer LL. Increased Mortality and Altered Immunity in Neonatal Sepsis Produced by Generalized Peritonitis. Shock. 2007 Dec;28(6):675-683. 

14.     Delano MJ, Scumpia PO, Weinstein JS, Coco D, Nagaraj S, Kelly-Scumpia KM, O'Malley KA, Wynn JL, Antonenko S, Al-Quran SZ, Swan R, Chung CS, Atkinson MA, Ramphal R, Gabrilovich DI, Reeves WH, Ayala A, Phillips J, Laface D, Heyworth PG, Clare-Salzler M, Moldawer LL. MyD88-Dependent Expansion of an Immature GR-1+CD11b+ Population Induces T-Cell Suppression and TH2 Polarization in Polymicrobial Sepsis. J Exp Med. 2007 Jun 11; 204(6):1463-74. Epub 2007 Jun 4 

15.     Iwakuma, N., Sharma, P., Delano, M.J., Moldawer, L., Moudgil, B., Grobmyer, S.R. Differential Uptake of PEG-FITC Silica Nanoparticles by Human Breast Cancer Cells and Normal Human Breast Epithelial Cells. NSTI Proceedings 2:348-349, 2007. 

16.     Scumpia PO, Delano MJ, Kelly KM, O’Malley KA, Efron PA, McAuliffe PF, Brusko T, Ungaro R, Barker T, Wynn JL, Atkinson MA, Reeves WH, Clare-Salzler MJ, Moldawer LL. Increased natural regulatory T cells and their suppressor activity does not influence mortality in murine polymicrobial sepsis. Journal of  Immunol 2006 Dec 1; 177(11) 

17.     Cuenca AG, Jiang H, Hochwald SN, Delano M, Cance WG, Grobmyer SR. Emerging Implications of Nanotechnology on Cancer Diagnostics and Therapeutics. Cancer. 2006 Aug 1;107(3):459-66 

18.     Delano MJ, Moldawer LL. The Origins of Cachexia in Acute and Chronic Inflammatory Diseases. Nutr Clin Pract. 2006 Feb;21(1):68-81

19.     Dempsey DT, Delano M, Bradley K, Kolff J, Fisher C, Caroline D, Gaughan J, Meilahn JE, Daly JM. Laparoscopic esophagomyotomy for achalasia: does anterior hemifundoplication affect clinical outcome? Annals of Surgery. June 2004; 239:6 

20.      Duffy JP, Delano MJ, Reber HA: Pancreatic Surgery. Current Opinion in Gastroenterology: 2002; 18:568-573. 

Published Abstracts: 

1.   Winfield RD, Delano MJ, Lottenberg L, Cendan JC, Moldawer LL, Maier RV, Cuschieri J.  “Traditional Resuscitative Practices Fail to Resolve Metabolic Acidosis in Morbidly Obese Patients Following Severe Blunt Trauma”.  Accepted Abstract: Oral Presentation, Annual Meeting of the Eastern Association for the Surgery of Trauma, January 13 – 17, Disney Yacht & Beach Club, Orlando, FL, 2009  

2.  Winfield RD, Delano MJ, Lottenberg L, Cendan JC, Moldawer LL, Maier RV, Cuschieri J.  “Traditional Resuscitative Practices Fail to Resolve Metabolic Acidosis in Morbidly Obese Patients Following Severe Blunt Trauma”.  Oral Presentation, Resident/Fellow Paper Competition, Annual Meeting of the Florida Committee on Trauma, Orlando, FL. October 24, 2008. Winner, Best Clinical Paper. 

3.  Matthew J. Delano, Philip O. Scumpia, Kindra M. Kelly-Scumpia, Robert D. Winfield, James Wynn, Reuben Ramphal, Wesley H. Reeves, Michael Clare-Salzler, E. Richard Stanley, Robert M. Strieter, Lawrence L. Lottenberg, and Lyle L. Moldawer. Myeloid Derived Suppressor Cell Expansion Is Dependent on CXCL12 Mediated Common Myeloid Progenitor Splenic Accumulation During Sepsis. Poster Presentation, Annual Meeting of the American Association for the Surgery of Trauma, Maui, HI. September 23, 2008 

4.  Winfield RD, Delano MJ, Cuschieri J, Dixon D, Schierding W, Cendan JC, Baker HV, Maier RV, Cobb JP, Moldawer LL.  “Initial Genomic Response Does Not Predict Differences in Outcome Between Obese and Normal Weight Patients Following Severe Blunt Trauma”.  Poster Presentation, Annual Meeting of the American Association for the Surgery of Trauma, Maui, HI. September 23, 2008 

5.  James L. Wynn, Philip O. Scumpia, Robert D. Winfield, Matthew J. Delano, Kindra M. Kelly-Scumpia, and Lyle L. Moldawer. Defective Neonatal Innate Immunity Causes Poor Sepsis Outcome, But Is Overcome By Select Toll-Like Receptor Agonist. Abstract and Poster Presentation 31st Annual Meeting of the Shock Society. Shock 2008 June (29)1:96. Supplement 

6.  Kindra M. Kelly-Scumpia, Philip O. Scumpia, Jason S. Weinstein, Matthew J. Delano, James L. Wynn, Drake Laface, Paul G. Heyworth, and Lyle L. Moldawer. Polymicrobial Sepsis Activates B Cells Through A Type 1 Interferon Dependent But MyD88 Independent Pathway. Abstract and Poster Presentation 31st Annual Meeting of the Shock Society. Shock 2008 June (29)1:98. Supplement 

7.  Matthew J. Delano, Robert D. Winfield, Philip O. Scumpia, James L. Wynn, Kindra M. Kelly-Scumpia, Robert M. Strieter, and Lyle L. Moldawer. Stromal Cell Derived Factor -1 Mediates Myeloid Derived Suppressor Cell Expansion During Polymicrobial Sepsis. Abstract and Poster Presentation 31st Annual Meeting of the Shock Society. Shock 2008 June (29)1:79. Supplement 

8.  Winfield RD, Delano MJ, Dixon D, Schierding W, Leek JT, Cendan JC, Hayden D, Lopez MC, Baker HV, Cobb JP, Moldawer LL, Maier RV, Cuschieri J.  “Initial Genomic Response does not Predict Outcome Between Obese and Normal Weight Patients Following Severe Blunt Trauma.”  Poster Presentation, 7th Annual Colloquium of the International Sepsis Forum, Chapel Hill, NC. May 13, 2008 

9.  Winfield RD, Delano MJ, Moldawer LL.  “The Role of Myeloid Derived Suppressor Cells in Cancer Cachexia.”  Poster Presentation, University of Florida Department of Surgery Research Day, Gainesville, FL. April 18, 2008 

10.  Winfield RD, Delano MJ, Lottenberg L, Cendan JC, Moldawer LL, Maier RV, Cuschieri J.  “Early Resuscitative Practices Fail to Correct Metabolic Acidosis in Morbidly Obese Trauma Patients.”  Oral Presentation, University of Florida Department of Surgery Research Day, Gainesville, FL.  April 18, 2008 Winner, Best Clinical Abstract Award. 

11.  Winfield RD, Moldawer LL, Scumpia PO, Wynn JL, Delano MJ, O'Malley KA, Moreno CO, Cance WG, Beierle EA.  “Focal Adhesion Kinase in Necrotizing Enterocolitis”.  Poster Presentation, Surgical Section Annual Meeting of the American Academy of Pediatrics, San Francisco, CA. October 27, 2007.  

12.  M.J. Delano, G.M. Janelle, P.O. Scumpia, K. O’Malley, R. Ungaro, C.L. Tannahill, E.D. Staples, T. Martin, L.L. Moldawer, and P.J. Hess. Aprotinin Attenuates The Immuno-inflammatory Response And Alters Blood Monocyte Gene Expression Following Cardiopulmonary Bypass. Surgery Research Symposium, Award Received: April 20, 2007, Department of General Surgery, University of Florida School of Medicine, Gainesville, FL. 

13.  MJ Delano M.D; CA Garces MD; WG Cance MD; SN Hochwald MD; SR Grobmyer MD. Preoperative Predictors of Intraoperative Blood Transfusion Requirement for Patients undergoing Pancreaticoduodenectomy.  Accepted Abstract and Poster Presentation, AHPBA Annual Meeting, April 19-22, 2007. 

14.  Steven N. Hochwald, Stephen R. Grobmyer, Eleanor Curran, Matthew Delano, Alan W. Hemming, William G. Cance, Stephen B. Vogel. Braun enteroenterostomy is associated with reduced delayed gastric emptying and early resumption of oral feeding following pancreaticoduodenectomy. Accepted Abstract and Poster Presentation, AHPBA Annual Meeting, April 19-22, 2007. 

15.  Delano, M.J., Scumpia, P.O., O’Malley, K., Wynn, J., Winfield, R. and Moldawer, L.L. Sepsis Reprograms Bone Marrow Hematopoesis Toward The Myeloid Linage In A MyD88 And TRIF Dependent Manner. Accepted Abstract and Oral Presentation. 7th World Congress on Trauma, Shock, Inflammation and Sepsis – TSIS 2007, March 13-17, 2007, Munich, Germany. 

16.  Wynn, JL, Scumpia, PO, Winfield, RD, Delano, MJ, O’Malley, K, Ungaro, R, Abouhamze, A, Moldawer, LL. Improved Survival in Neonatal Mice with Sepsis Following TLR Agonist Treatment. Accepted Abstract and Oral Presentation. 7th World Congress on Trauma, Shock, Inflammation and Sepsis – TSIS 2007, March 13-17, 2007, Munich, Germany. 

17.  Scumpia PO, Delano MJ, Kelly KM, Weinstein JS, Clare Salzler MJ, Moldawer LL. Treatment with anti-GITR agonistic antibody corrects T cell dysfunction and improves survival in murine sepsis. Accepted Abstract and Oral Presentation. 7th World Congress on Trauma, Shock, Inflammation and Sepsis – TSIS 2007, March 13-17, 2007, Munich, Germany.  

18.  MJ Delano M.D; CA Garces MD; WG Cance MD; SN Hochwald MD; SR Grobmyer MD. Preoperative Predictors of Intraoperative Blood Transfusion Requirement for Patients undergoing Pancreaticoduodenectomy.  Accepted Abstract and Poster Presentation, AHPBA Annual Meeting, April 19-22, 2007. 

19.  Matthew J. Delano, M.D., Philip O. Scumpia, B.S., Ricardo Ungaro, B.S.,  Cynthia L. Tannahill, M.S., Kerri O’ Malley, Ph.D., Gregory M. Janelle, M.D., Amer Abouhamze, M.S., Thomas D. Martin, M.D., Edward D. Staples, M.D., Walter W. Scott, M.D., Lyle L. Moldawer, Ph.D., Philip J. Hess, M.D. Genomic and Proteomic Responses after Cardiopulmonary Bypass Indicate Innate Immune System Dysfunction. Accepted Abstract and Oral Presentation Society of Thoracic Surgeons Annual Meeting San Diego, CA. January 28-30, 2007. 

20.  Azra Bihorac, Matthew Delano, Andrea Gabrielli, Avery B. Nathens, Ronald V. Maier, A. Joseph Layon, and Lyle L Moldawer. Incidence, clinical predictors, and outcome of acute kidney injury among trauma patients. Accepted Abstract and Poster Presentation, American Society of Nephrology 39th Annual Meeting and Scientific Exposition, November 14-19, 2006. San Diego, CA.                    

21.  Matthew J. Delano, M.D., Azra Bihorac, M.D., Philip O. Scumpia, B.S., Avery B, Nathens, M.D., Ronald G. Maier, M.D., Joseph A. Layon, M.D., Lyle L. Moldawer, Ph.D. Early Genomic and Proteomic Changes in Trauma Patients With Acute Kidney Injury Suggest Early Immune Dysfunction. Accepted Abstract and Poster Presentation, Innate Immunity Meeting, SLB, ISER, San Antonio, TX.  November 9-11, 2006. 

22.  Qizhi Zhang, Ph.D., Matthew Delano, M.D., Huabei Jiang, Ph.D., Stephen R. Grobmyer, M.D. Gold Nanoparticles as a Contrast Agent for High Resolution in Vivo Imaging Using Photoacoustic Tomography. Accepted Abstract and Oral Presentation, International Nanoparticle Congress, San Francisco, CA. November 1-3, 2006. 

23.  MJ Delano, PO Scumpia, K O’Malley, J Wynn, R Ungaro, C Tannahill, L Lottenberg, LL Moldawer. Immature Myeloid Cell Activity in a Murine Polymicrobial Sepsis Model. Accepted Abstract and Poster Presentation, AAST Meeting, New Orleans, LA September 28-30, 2006. 

24.  M. Delano, P. Scumpia, K. O’Malley, J. Wynn, R. Ungaro, L. Moldawer. Regulation of GR-1+CD11b+ Myeloid Suppressor Cells in Murine Polymicrobial Sepsis. Shock 2006 June (25)1:64. Supplement. 

25.  Scumpia PO, Delano MJ, Moldawer LL. Regulatory T cells are increased but do not participate in mortality in murine polymicrobial sepsis. Shock 2006 June (25)1:8. Supplement. 

26.  Scumpia PO, Weinstein JS, Delano MJ, Kelly KM, Reeves WH, Clare-Salzler MJ, Moldawer LL. B cell dysfunction in sepsis is T cell dependent. Leuk Biol Supplement (accepted). 

27.  M. Delano, P. Scumpia, K. O’Malley, J. Wynn, R. Ungaro, C. Tannahill, A. Abouhamze, L. Moldawer. Regulation of GR-1+CD11b+ Myeloid Suppressor Cells in Murine Polymicrobial Sepsis. Oral Presentation: Department of Surgery Research Day, University of Florida, March 31, 2006. 

28.  Daniel T. Dempsey, M.D., Matthew Delano, M.D., Kevin Bradley, M.D., Jeffrey Kolff, M.D., Carol Fisher, B.A., Dina Caroline, M.D.*, John Gaughan, Ph.D.#, John E. Meilahn, M.D., John M. Daly, M.D.: Laparoscopic esophagomyotomy for achalasia: does anterior hemifundoplication affect clinical outcome?: Departments of Surgery, Radiology*, and Biostatistics#, Temple University School of Medicine, Philadelphia, PA. Abstract Presented: Southern Surgical Association Meeting, December, 2003, Hot Springs, VA. 

29.  Delano MJ, Duffy JP, Fisher C, Hines OJ, Reber HA: Cellular and Molecular Expression of CXCR4 in Human Pancreatic Cancer Cell Lines: Department of Surgery, The David Geffen School of Medicine at the University of California, Los Angeles, CA. Abstract and Poster Presentation: March 28, 2003, Association of Academic Surgery 2003 Student Research Award (AWARD RECIPIENT). 

30.  Delano MJ, Duffy JP, Fisher C, Hines OJ, Reber HA: Cellular and Molecular Expression of CXCR4 in Human Pancreatic Cancer Cell Lines: Department of Surgery, The David Geffen School of Medicine at the University of California, Los Angeles, CA; Department of Surgery, Temple University School of Medicine, Philadelphia, PA. Abstract and Poster Presentation: April 16, 2003, Temple University School of Medicine Research Day 2003 (AWARD RECIPIENT).     

31.  JP Duffy, HA Reber, MN Wente, G Eibl, Y Okada, M Delano, OJ Hines: Vitronectin stimulates mitogen-activated protein kinase activity in human pancreatic cancer cells: Department of Surgery, The David Geffen School of Medicine at the University of California, Los Angeles, CA. Poster Presentation: 6th Annual Longmire Surgical Society Scientific Day, UCLA, March 22, 2002. 

32.  Eibl G, Okada Y, Reber HA, Duffy J, Delano M, Wente MN, Hines OJ: Prostaglandin E2 is mitogenic and increases VEGF in human pancreatic cancer cells: Department of Surgery, The David Geffen School of Medicine at the University of California, Los Angeles, CA. Abstract Accepted: American College of Surgeons 88th Annual Clinical Congress, San Francisco, CA, October 6-10, 2002. 

33.  Eibl G, Okada Y, Reber HA, Duffy J, Delano M, Wente MN, Hines OJ: PPAR-γ stimulates plasminogen activator inhibitor-1 and decreases urokinase-type plasminogen activator levels in human pancreatic cancer cells: Department of Surgery, The David Geffen School of Medicine at the University of California, Los Angeles, CA. Oral Presentation Accepted: Association of Academic Surgery 36th Annual Meeting, Boston, MA, November 7-9, 2002. 

34.  Duffy J, Eibl G, Okada Y, Delano M, Reber H, Hines J: Vitronectin stimulates p44/42 mitogen-activated protein kinase in human pancreatic cancer cells: Department of Surgery, The David Geffen School of Medicine at the University of California, Los Angeles, CA. Oral Poster Presentation Abstract Accepted: Association of Academic Surgery 36th Annual Meeting, Boston, MA, November 7-9, 2002. 

35.  John P. Duffy, Howard A. Reber, Guido Eibl, Yuji Okada, Moritz N. Wente, Matthew J. Delano, Oscar J. Hines: Evidence for vitronectin autocrine regulation in pancreatic cancer cells. Department of Surgery, The David Geffen School of Medicine at the University of California, Los Angeles, CA. Abstract and Poster Presentation Accepted: American Pancreatic Association Annual Meeting, November 14-15, 2002. 

36.  Okata Y, Hines OJ, Wente MN, Eibl G, Duffy JP, Delano MJ, Reber HA: Mutation Analysis of the RET receptor in human pancreatic cancer: Department of Surgery, The David Geffen School of Medicine at the University of California, Los Angeles, CA. Abstract Accepted: Association of Academic Surgery 36th Annual Meeting, Boston, MA, November 7-9, 2002. 

37.  Delano MJ, Gravelle S: Assembly of a Teltron X-ray Diffractometer to conduct single crystal and silicon powder analysis: Chemistry Department, Saint Vincent College, Latrobe, PA. Abstract and Poster Presentation: American Chemical Society National Convention 1996, New Orleans, LA. 

BOOK CHAPTERS:

 1.  Armstrong, J.A., Delano, M.J. TRAUMA. In Tribble, C., Hobson, C., and Thaemert, N. editors, ICU Recall, 3rd Edition, Philadelphia, PA: Lippincott Williams & Wilkins 2008.

2. Delano, M.J., Zolack, J. INFECTION AND SEPSIS, In Tribble, C., Hobson, C., and Thaemert, N. editors, ICU Recall, 3rd Edition, Philadelphia, PA: Lippincott Williams & Wilkins 2008

Doctoral Dissertation:

“Impact of Myeloid Derived Suppressor Cells During Polymicrobial Sepsis”

Dissertation Defense: Wednesday, March 26, 2008
Written Dissertation Acceptance: Monday, April 21, 2008
Mentor: Lyle L. Moldawer, Ph.D., Laboratory of Inflammation Biology and Surgical Science
Committee Chair: Michael Clare-Salzler, M.D.

 

Invited Grand Rounds:

1.)  Impact of Immature Myeloid Cells in Sepsis.

University of Florida, Department of Surgery, Grand Rounds, November 15, 2006. 

2.)  Splenic Injuries and Contemporary Management.

Trauma and Critical Care Grand Rounds, Department of Surgery, University of California at Davis School of Medicine, Sacramento, CA, November 15, 2002 

 

Demonstrations and Presentations

 

1.      Delano MJ, Mozingo DW: Morbidity and Mortality, Trauma, Burn, and Emergency Surgery

Morbidity and Mortality Conference, Department of Surgery, University of Florida, Gainesville, FL, March 30, 2005 

2.      Delano MJ, Paidas CN: Rectal Prolapse following Posterior Sagittal Repair for Ano Rectal Malformation in Children.

Division of Pediatric Surgery, University of South Florida, Tampa General Hospital
Division of Pediatric Surgery, Department of Surgery, University of Florida, Shands Hospital
Chairman’s Conference, Department of Surgery, University of Florida, Gainesville, FL, March 23, 2005 

3.      Delano MJ: Evaluation of Low Anterior Resection vs. Abdominoperineal Curative Resection for Cancer of the Lower Rectum.

      Chairman’s Conference, Department of Surgery, University of Florida, Gainesville, FL, June 9, 2004 

4.      Delano MJ: Carotid Artery Dissection.

      Vascular Surgery Conference, Division of Vascular Surgery, Department of Surgery, The David Geffen School of Medicine at the University of California, Los Angeles, CA,October 3, 2002 

5.      Duffy JP, Delano MJ: Explained and performed a laparoscopic cholecystectomy and demonstrated bovine biliary anatomy for area high school students from Los Angeles, CA

The David Geffen School of Medicine at the University of California, Los Angeles, CA, April, 2002

 
 

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