| Priscilla F.
McAuliffe, M.D., Ph.D.
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RESEARCH INTERESTS:
1. McAuliffe PF, Gold MS, Bajpai L, Merves ML, Frost-Pineda K, Pomm RM, Goldberger BA, Melker RJ, Cendán JC. Second-hand exposure to aerosolized intravenous anesthestics propofol and fentanyl may cause sensitization and subsequent opiate addiction among anesthesiologists and surgeons. Accepted to Medical Hypotheses. 2. Camp ER, McAuliffe PF, Gilroy JS, Morris CG, Lind DS, Mendenhall NP, Copeland EM. Minimizing local recurrence following breast conserving therapy utilizing intra-operative shaved margins to determine pathologic tumor clearance. Accepted to Journal of the American College of Surgeons. 3. McAuliffe PF, Cance WG. Preemptive Surgery. Accepted to Surgery. 4. McAuliffe PF, Murday ME, Efron PA, Scumpia PO, Abouhamze A, Tannahill CL, Ungaro R, Hutchins B, LaFace D, Moldawer LL. Dose-dependent improvements in outcome with adenoviral expression of interleukin-10 in a murine model of multisystem organ failure. Gene Therapy. 2005; advance online publication:1-7. 5. Scumpia PO, McAuliffe PF, O'Malley KA, Ungaro R, Uchida T, Matsumoto T, Remick DG, Clare-Salzler MJ, Moldawer LL, Efron PA. CD11c+ dendritic cells are required for survival in murine polymicrobial sepsis. Journal of Immunology. 2005;175(5):3282-6. 6. Delman KA, Zager JS, Bennett JJ, Malhotra S, Ebright MI, McAuliffe PF, Halterman MW, Federoff HJ, Fong Y. Efficacy of multiagent herpes simplex virus amplicon-mediated immunotherapy as adjuvant treatment for experimental hepatic cancer. Annals of Surgery. 2002; 236(3):337-42. 7. Cozzi PJ, Malhotra S, McAuliffe P, Kooby DA, Federoff HJ, Huryk B, Johnson P, Scardino PT, Heston WD, Fong Y. Intravesical oncolytic viral therapy using attenuated, replication-competent herpes simplex viruses G207 and NV1020 is effective in the treatment of bladder cancer in an orthotopic syngeneic model. FASEB Journal. 2001; 15(7):1306-1308. 8. McAuliffe PF, Jarnagin WR, Johnson P, Delman KA, Federoff H, Fong Y. Effective treatment of pancreatic tumors with two multimutated herpes simplex oncolytic viruses. Journal of Gastrointestinal Surgery. 2000; 4(6):580-8. 9. Delman KA, Bennett JJ, Zager JS, Burt BM, McAuliffe PF, Petrowsky H, Kooby DA, Hawkins WG, Horsburgh BC, Johnson P, Fong Y. Effects of preexisting immunity on the response to herpes simplex-based oncolytic viral therapy. Human Gene Therapy. 2000; 11(18):2465-72. 10. Bennett JJ, Kooby DA, Delman K, McAuliffe P, Halterman M, Brennan M, Federoff H, Fong Y. Antitumor efficacy of regional oncolytic viral therapy for peritoneally disseminated cancer. Journal of Molecular Medicine. 2000; 78(3):166-74. 11. McGuire DE, McAuliffe P, Heinemann MH, Rahhal FM. Efficacy of the ganciclovir implant in the setting of silicone oil vitreous substitute. Retina. 2000; 20(5):520-3. 12. McAuliffe PF, Heinemann MH. Use of pneumatic retinopexy to delay surgical repair of a retinal detachment associated with the ganciclovir intraocular device. Ophthalmic Surgery and Lasers. 1998; 29(3):244-6. 13. McAuliffe PF, Hall MJ, Castro-Malaspina H, Heinemann MH. Use of the ganciclovir implant for treating cytomegalovirus retinitis secondary to immunosuppression after bone marrow transplantation. American Journal of Ophthalmology. 1997; 123(5):702-3.
1. McAuliffe PF, Efron PA, Scumpia PO, Uchida T, Mutschlecner SC, Rout WR, Moldawer LL, Cendan JC. Varying blood monocyte and dendritic cell responses after laparoscopic versus open gastric bypass surgery. 10th World Congress of the International Federation for the Surgery of Obesity, August 16, 2005. 2. Turner PC, McAuliffe P, Moyer RW. Poxvirus serpins. 4th International Symposium on Serpin Structure, Function and Biology, June 7, 2005. 3. Scumpia P, Efron P, McAuliffe P, Uchida T, Ungaro R, Tannahill C, Clare-Salzler M, Moldawer L. Loss of CD11c-expressing dendritic cells increases mortality in murine polymicrobial sepsis. Shock, June 4, 2005. 4. McAuliffe PF, Byrne BJ, Moldawer LL, Lucas A, Moyer RW. Poxvirus serpin mediated amelioration of chronic inflammation in a mouse carotid ligation model. NIH/NIAID Biodefense - 5th Annual Orthopox Research Group Meeting, April 21, 2005. 5. McAuliffe PF, Moyer RW, Lewis MA, Zolotukhin I, Lucas A, Byrne BJ, Ozaki CK, Moldawer LL. Viral serine protease inhibitors, SERP1 and SPI-3, mitigate intimal hyperplasia either directly or when expressed by recombinant adeno-associated virus-mediated gene transfer. NIH/Society for Vascular Surgery - Research Initiatives in Vascular Disease Conference, April 8, 2005. 6. McAuliffe PF. Resident experience with patient safety curriculum and Root Cause Analysis at the University of Florida. National Center for Patient Safety Conference, March 6, 2005. 7. Efron PA, Matsumoto T, Tsujimoto H, McAuliffe PF, Scumpia P, Moldawer LL, Fujita S, Foley D, Hemming A. Alterations in circulating dendritic cells and monocytes following hepatectomy may affect systemic immunity. Society of University Surgeons, February 11, 2005. 8. McAuliffe PF, presenting for: Cendan JC, Frost-Pineda K, Melker R, Dennis D, Morey T, Pomm R, Gold MS. Addiction: An occupational hazard related to the operating room? Society of University Surgeons Residents' Conference, February 10, 2005. 9. McAuliffe PF, Stevens AO. Resident experience with patient safety curriculum and Root Cause Analysis at the University of Florida. National Center for Patient Safety Conference, January 11, 2005. 10. Efron PA, Scumpia PO, Matsumoto T, Tsujimoto H, Tschoeke SK, McAuliffe PF, Ungaro R, Moldawer LL. T regulatory cells are increased druing murine polymicrobial sepsis. (Oral Poster) 6th World Congress on Trauma, Shock, Inflammation and Sepsis, March 5, 2004. 11. McAuliffe PF, Moldawer LL, Cresawn K, Zolotukhin I, Bray E, Berceli SA, Ozaki CK, Byrne BJ. Elafin over-expression and rAAV-mediated gene transfer strategies for neointimal hyperplasia. American College of Surgeons Surgical Forum, October 22, 2003. 12. Jarnagin W, McAuliffe P, Delman K, Fong Y. Effective treatment of pancreatic tumors with two multimutated herpes simplex viruses. Society for Surgery of the Alimentary Tract, May 20-24, 2000. 13. Bennett J, Kooby D, Delman K, McAuliffe P, Halterman M, Federoff H, Fong Y. Peritoneal delivery of oncolytic herpes viral therapy is effective for gastric carcinomatosis. AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics: Discovery, Development and Clinical Validation, November 16-19, 1999. 14. McAuliffe P, Kooby D, Bennett J, Carew J, Cozzi P, Delman K, Fong Y. Comparison of two oncolytic viruses (G207 and NV1020) as therapy for experimental solid tumors. American College of Surgeons Surgical Forum, October 10-15, 1999. 15. McGuire DE, Rahhal FM, McAuliffe PF, Heinemann MH. Efficacy of the ganciclovir intraocular device in the setting of silicone oil vitreous substitute. Investigative Ophthalmology and Visual Science 1997; 38(4): 4283. 16. Heinemann MH, McAuliffe P, Ursea R, Rahhal FM. Rhegmatogenous retinal detachment associated with the ganciclovir intraocular device. Investigative Ophthalmology and Visual Science 1997; 38(4): 3415.
1. Turner PC, McAuliffe PF, Moyer RW. Viral serpins. In: Silverman GA, ed. The Serpinopathies: Molecular and Cellular Aspects of Serpins and their Disorders. Hackensack, NJ: World Scientific Publishing Co, Inc. 2005. 2. McAuliffe PF, Moldawer LL. Endotoxin and cytokines in liver and biliary tract disease. In: DeMatteo RP and Blumgart LH, eds. Surgery of the Liver, Bilary Tract and Pancreas, 4th Ed. Philadelphia, PA: Elsevier Inc. 2005. 3. McAuliffe PF, Mozingo DW. Inhalation injury and ventilator management. In: Soper NJ, Saffle JR, eds. Problems in General Surgery: Thermal Injuries. Philadelphia, PA: Lippincott, Williams and Wilkins 2002; 20(1): 97-105.
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