Charles T. Klodell, MD

Associate Professor
Thoracic and Cardiovascular Surgery
email: klodell@surgery.ufl.edu
phone: 352-273-5507
fax: 352-273-5513

Awards and Professional Interests - Research/Clinical Interests
Research Projects - References - Biosketch - Links

Awards and Professional Interests
  • Alpha Omega Alpha Honor Medical Society
  • Phi Kappa Phi Honor Medical Society
  • Who’s Who Among Students in American Universities and Colleges
  • Member - Society of Thoracic Surgeons
  • Member - American College of Chest Physicians
  • Member - Southern Thoracic Surgical Association

Research/Clinical Interests
  • Mitral and Aortic valve repair including Minimally Invasive Valve surgery
  • Ventricular Assist Devices and Destination Therapy
  • MAZE and Mini Maze procedures for atrial fibrillation
  • Endoscopic Thoracic Sympathectomy (ETS) and the treatment of Hyperhidrosis (minimally invasive approach)
  • Stent Graft Repair of Thoracic Aneurysms (Minimally Invasive)
  • Surgical Treatment of Complex Aortic Diseases
  • Surgery for Advanced Heart Failure (DOR procedure and ventricular restoration)
  • Marfan's Syndrome and surgery of the Aortic Root
  • Utilization of Advanced Technologies to reduce the invasiveness of Thoracic and Cardiovascular Surgeries
  • Blood Conservation in Thoracic and Cardiovascular Surgery
  • Cardiac Transplantation
  • Adult Congential Cardiac Surgery
  • Aortic Root Surgery with emphasis on Valve Preservation
  • Bloodless Surgery
  • Advanced Pain Management for Patient Comfort
Research Projects
  • Evaluation of Genomic Activation and Local and Systemic Inflammation, and its role in the progression and reversal of severe Congestive Heart Failure
  • Pulsatility Index as an indicator of adequate sympathectomy for Hyperhidrosis
  • Development of a Novel Ventricular Assist Device (Patent pending)
  • Phase II trials of several Ventricular assist devices under FDA evaluation
  • Multimodality Perioperative Pain Management and effect on Patient Satisfaction Scores
  • Development of Acoustic Monitoring tools to maintain good LVAD function (Patent Pending)

References
  1. Kim, T, Martin, TD, Lee, WA, Hess, PJ, Klodell CT, Tribble CG, Feezor RJ, Beaver TM; Evolution in the management of the total thoracic aorta. J Thorac Cardiovasc Surg 2009; 137:627.
  2. Feezor, RJ, Hess PJ, Martin TD, Klodell CT, Beaver TM, Lottenberg L, Martin LC, Lee WA; Endovascular Treatment of Traumatic Thoracic Aortic Injuries. In Press JACC 2009.
  3. Hess PJ, Harman PK, Klodell CT, Beaver TM, Bologna MT, Mikhail PS, Tribble CG, Martin TD; Early outcomes using the Florida Sleeve repair for correction of aortic insufficiency due to root aneurysms. Ann Thorac Surg 2009; 87:1161.
  4. Husain SA, Wallis G, Fricker FJ, Bleiweis MS, Staples ED, Klodell CT, Brown JW, Turrentine MW; Ventricular Assist Device Implantation in the Pediatric Population: Does Pump Size Selection and Associated Hemodynamics Impact Outcomes? ASAIO Sept/Oct 2008 Vol. 54 Issue 5 pp. 474-79.
  5. Schofield RS, Dorman SM, Aranda JM, Hill JA, Pauly DF, Klodell CT; Constrictive Pericarditis Presenting as a Calcified Anterior Pericardial Mass. In Press. Annals of Thoracic Surgery 2008.
  6. Feezor RJ, Martin TD, Hess PJ, Beaver TM, Klodell CT, Lee WA; Early Outcomes after Endovascular Management of Acute, Complicated Type B Aortic Dissection. J Vasc Surg 2009; 49:561.
  7. Feezor RJ, Martin TD, Hess PJ, Beaver TM, Klodell CT, Brown MP, Huber TS, Seeger JM, Lee WA; Extent of Aortic Coverage and Incidence of Spinal Cord Ischemia after TEVAR. Ann Thorac Surg 2008; 86:1809.
  8. Klodell CT; Video-assisted thoracoscopic left cardiac sympathetic denervation: a reliable minimally invasive approach for congenital long QT syndrome (Commentary). Klodell, CT; Invited commentary. Ann Thorac Surg 2008; 86:1958.
  9. Puwanant S, Klodell CT, Hamilton KK, Hill JA, Schofield RS, Cleeton T, Pauly DF, Aranda JM; Tricuspid Annular Motion as a Predictor of Severe Right Ventricular Failure Following Left Ventricular Assist Device Implantation. J Heart Lung Transplant 2008; 27:1102.
  10. Woo GW, Schofield RS, Pauly DF, Hill JA, Conti JB, Kron J, Klodell CT, Singh R, Aranda JM; Incidence, predictors, and outcomes of cardiac pacing after cardiac transplantation: an 11-year retrospective analysis. Transplantation 2008; 85 (8):1216-1218.
  11. Urdaneta F, Lobato EB, Beaver TM, Muehlschlegel JD, Kirby DS, Klodell CT, Sida A; Treating Pulmonary Hypertension Post Cardiopulmonary Bypass in Pigs: Milrinone vs. Sildenafil Analog. Perfusion 2008; 23:178.
  12. Aranda JM, Martin TD, Leach DD, Klodell CT; Reoperative Cardiac Surgery Following Long-Term Ventricular Support Therapy. J Heart Lung Transplant 2008; 27:789-791.
  13. Klodell CT, Aranda JM, Rayburn BK, McGiffin DC, Abraham WT, Sun B, Boehmer JP, Pae WE, Klein H, Huth C; Early Worldwide Surgical Experience with the Paracor HeartNet Cardiac Restraint Device. J Thorac Cardiovasc Surg 2008 Jan; 135(1):188-195.
  14. Klodell CT, Vlasak RM, Martin TD, Janelle G, Beaver TM; Impending aortic penetration following thoracolumbar spinal fixation. Journal of Long Term Effects of Medical Implants Vol 17, Issue 1, March, 2008.
  15. Mikhail P, Hess PJ, Klodell CT, Beaver TM, Lee WA, Tribble CG, Martin TD; A Technique for Closure of Thoracic Aortic Type I Endoleaks and Landing Zone Preparation. Ann Thor Surg 2008; 85:e 9-11.
  16. Muehlschlegel JD, Peng YG, Lobato EB, Hess PJ, Martin TD, Klodell CT; Temporary Biventricular Pacing Post Cardiopulmonary Bypass in Patients with Reduced Ejection Fraction. Journal of Cardiac Surgery; 23:4, 2008.
  17. Arnaoutakis GJ, Bihorac A, Martin TD, Hess PJ, Klodell CT, Ejaz AA, Garvan C, Tribble CG, Beaver TM; RIFLE criteria for acute kidney injury in aortic arch surgery; J Thorac and Cardiovasc Surg 2007; 134(6):1554-1560.
  18. Feezor RJ, Martin TD, Hess PJ, Klodell CT, Beaver TM, Huber TS, Seeger JM, Lee WA; Risk factors for perioperative stroke during thoracic endovascular aortic repairs. (TEVAR) J Endo Ther 2007; 14(4):568-573.
  19. Schofield RS, Aranda JM, Shoemaker SM, Pauly DF, Hill JA, Klodell CT; Cardiac Transplantation in Patients with Antiphospholipid Antibodies; Journal of Heart and Lung Transplantation, 2007; 26(3):299-301.
  20. Aranda, JM, McIntyre SE, Klodell CT, Schofield RS, Chaille PJ, Conti JB, Pauly DF, Hill JA; Initial Heart Rate and Systolic Blood Pressure Predict Outcomes in Chronic Heart Failure Patients Who are Evaluated for Cardiac Transplant; Clin Cardiol, 2007; 30:282-287.
  21. Klodell CT, McGiffin DC, Rayburn BK, Sun B, Abraham WT, Conte JV, Russell S, Pae W, Boehmer S, Aranda JM; Initial United States Experience with the Paracor HeartNet Myocardial Constraint Device for Heart Failure. J Thorac Cardiovasc Surg, 2007; Jan; 133(1):204-209.
  22. Schofield RS, Pierce GL, Klodell CT, Nichols WW, Aranda JM, Pauly DF, Hill JA, Braith RW; Central Arterial Stiffness is Increased in End-Stage Heart Failure Patients on Left Ventricular Assist Device Support; American Journal of Hypertension (AJH) 2007; 20:622-628.
  23. Feezor RJ, Huber TS, Martin TD, Beaver TM, Hess PJ, Klodell CT, Nelson PR, Berceli SA, Seeger JM, Lee WA; Perioperative Differences Between Endovascular Repair of Thoracic and Abdominal Aortic Diseases; J Vasc Surg 2007; 45(1):86-89.
  24. Klodell CT, Morey TE, Lobato EB, Aranda JM, Staples ED, Schofield RS, Hess PJ, Martin TD, Beaver TM; Effect of Sildenafil on Pulmonary Artery Pressure, Systemic Pressure, and Nitric Oxide Utilization in Patients with Left Ventricular Assist Devices; Ann Thorac Surg 2007; 83:68-71.
  25. Vazquez Sowell L, Kuhl EA, Sears SF, Klodell CT, Conti JB; Device Implant Technique and the Consideration of Body Image: Specific Procedures for Female ICD Patients; Journal of Women's Health, 2006; 15(7):830-835.
  26. Woo GW, Schofield RS, Klodell CT, Pauly DF, Hill JA, Aranda JM; Atrial fibrillation as a cause of left ventricular dysfunction after cardiac transplantation; J Heart Lung Transplant 2006; 25:131-133.
  27. Mathur A, Baz M, Staples ED, Bonnell M, Hess PJ, Klodell CT, Speckman J, Moldawer LL, Beaver TM; Cytokine profile following lung transplantation: correlation with allograft injury; Annals of Thoracic Surgery 2006; 81(5):1844-1850.
  28. Lobato EB, Beaver TM, Muehlschlegel JD, Kirby DS, Klodell CT, Sidi A; Treatment with phosphodiesterase inhibitors type III and V: milrinone and sildenafil is an effective combination during thromboxane-induced acute pulmonary hypertension 10.1093/bja/ael009. Br. J. Anaesth. 2006:ael009.
  29. Klodell CT, Staples ED, Aranda JM, Schofield RS, Hill JA, Pauly DF, Beaver TM; Managing the Post LVAD Patient; Congest Heart Fail 2006; 12(1):41-45.
  30. Klodell CT, Lobato EB, Willert JL, Gravenstein N; Oximetry-derived perfusion index for intraoperative identification of successful thoracic sympathectomy; Ann Thorac Surg 2005; 80:467-470.
  31. Hess PJ, Jr., Klodell CT, Beaver TM, Martin TD; The Florida sleeve: a new technique for aortic root remodeling with preservation of the aortic valve and sinuses; Ann Thorac Surg 2005; 80:748-750.
  32. Klodell CT, Jr.; Secondary pulmonary hypertension: a review of the cardiac causes; J Cardiovasc Nurs 2005; 20:119-123.
  33. Beaver TM, Herrbold FN, Hess PJ, Jr., Klodell CT, Martin TD; Transferring diagnosis versus actual diagnosis at a center for thoracic aortic disease; Ann Thorac Surg 2005; 79:1957-1960.
  34. Trachte AL, Lobato EB, Urdaneta F, Hess PJ, Klodell CT, Martin TD, Staples ED, Beaver TM; Oral sildenafil reduces pulmonary hypertension after cardiac surgery. Ann Thorac Surg 2005; 79:194-197; discussion 194-197.
  35. Klodell CT, Beaver TM, Clark D, Martin TD; Distal aortic perfusion during aortic arch reconstruction: another tool for the aortic surgeon. Ann Thorac Surg 2004; 78:2196-2198.
  36. Holt RL, Martin TD, Hess PJ, Beaver TM, Klodell CT; Jehovah's Witnesses requiring complex urgent cardiothoracic surgery. Ann Thorac Surg 2004; 78:695-697.
  37. Janelle GM, Klodell CT, Martin TD; Other potential solutions to facilitate thoracoabdominal aortic aneurysm repair when uncontrolled hemorrhage develops at the subclavian clamp site. Anesth Analg 2004; 98:555.
  38. Klodell CT, Richardson JD, Bergamini TM, Spain DA; Does cell-saver blood administration and free hemoglobin load cause renal dysfunction? Am Surg 2001; 67:44-47.
  39. Klodell CT, Martin RC, Allen JA, Polk HC; Advanced Surgical Technology Experience – Valuable to the Basic Education of General Surgery Residents. Bull Am Col Surg June 2001; 86(6):11-15.
  40. Klodell CT, Caroll M, Carrillo EH, Spain DA; Routine intragastric feeding following traumatic brain injury is safe and well tolerated. Am J Surg 2000; 179:168-171.
  41. Klodell CT, Pokorny RM, Carrillo EH, Heniford BT; Exercise-induced compartment syndrome: case report. Am Surg 1996; 62:469-471.

 
Biosketch
Education
1987 - 1991B.S., Gannon University Erie,Pennsylvania Major:Chemistry Summa Cum Laude
1991-1995M.D.,University of Louisville School of Medicine Louisville, Kentucky Summa Cum Laude
 
Postdoctoral Training
1995 - 1996Straight Surgical Internship University of Louisville
1996 - 2000General Surgery Residency University of Louisville
2000 - 2002Cardiothoracic Fellowship University of Florida
2007Heart Valve Club / La Club Mitrale, Georges Pompedeu Hospital, Paris, (Dr. Alain Carpentier)
 
Academic Appointments
2002- 2008Assistant Professor of Surgery, Division of Thoracic and Cardiovascular Surgery, University of Florida
2004-PresentAffiliate Assistant Professor of Anesthesiology
2002 – PresentDirector – Mechanical Circulatory Support
2005-PresentAffiliate Assistant Professor of Pediatrics
1999-2000Quality Surgical Solutions – Data analyst and cost Containment strategist
2003-PresentDirector - Cardiac Intensive Care Unit
2008 - presentAssociate Professor of Surgery, Division of Thoracic and Cardiovascular Surgery, University of Florida
2005 - PresentAffiliate Assistant Professor of Biomedical Engineering
2005 - PresentAssociate Medical Director, Gainesville Fire and Rescue

 
Links
  1. Mitral Valve Repair (http://www.sts.org/doc/4108)
    General description of Mitral Valve Repair

  2. Hyperhidrosis Center (http://www.surgery.ufl.edu/tcv/hyperhidrosis.asp)
    Minimally Invasive treatment of hyperhidrosis

  3. More Hyperhidrosis Information (http://www.sts.org/doc/4097)
    Patient Information about Hyperhidrosis

  4. Aortic Surgery (http://www.surgery.ufl.edu/tcv/aortic_surgery.asp)
    U F.A.S.T - University of Florida Aortic Surgery Team

  5. Ventricular Assist Devices (http://www.surgery.ufl.edu/tcv/heart_failure.asp)
    U of F Mechanical Circulatory Support Program

  6. MAZE procedure for Atrial Fibrillation (http://www.sts.org/doc/4511)
    Description of Surgical procedure for atrial fibrillation

  7. Mitral Valve Replacement (http://www.sts.org/doc/4102)
    General description of Mitral Valve Replacement

  8. Aneurysms and Treatment (http://www.sts.org/doc/3621)
    Society of Thoracic Surgeons Website on Aneurysms

  9. Aortic Valve Surgery (http://www.sts.org/doc/3621)
    General description of Aortic Valve Replacement

  10. Mini Maze Operation (http://www.minimaze.org)
    General description of the "minimaze" minimally invasive pulmonary vein isolation for atrial fibrillation

  11. Society of Thoracic Surgeons Patient Information Website (http://www.sts.org/doc/2189)
    Offers information and illustrations that help explain a variety of cardiovascular conditions and operations

  12. So How About After My Surgery? (http://www.sts.org/doc/3563)
    What to expect after your heart surgery

  13. LVADs Save Lives (http://www.sciencedaily.com/videos/2005-05-06/)
    This is a short video of one of our patients supported with LVAD.


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